Copyright 2023 American Academy of Family Physicians. Divergent and conflicting opinions are common and perceived as health scientific discourse that results in a thoughtful, relevant systematic review. They can grow as a . If you have symptoms of uterine fibroids, your doctor may order these tests: Ultrasound. AskMayoExpert. We will use multilevel models, which boost the power of the analysis by sharing strengths across subgroups for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis) to explore heterogeneity if there are a sufficient number of studies. The embolic agents then flow to the fibroids and lodge in the arteries that feed them. Uterine Fibroids: Causes, Treatment, and Prevention - WebMD Another selective estrogen receptor modulator, raloxifene (Evista), has also shown inconsistent results, with two of three studies included in a Cochrane review showing significant benefit.57, Hysterectomy. The domains of consistency and precision will be assessed based on the direction and variation of the estimates. Obstetrics and Gynecology Clinics of North America. Older women in or entering menopause may have a higher cancer risk, and women who are no longer concerned about preserving their fertility have additional treatment options for fibroids. Expectant management is recommended for asymptomatic patients because most fibroids decrease in size during menopause. Uterine leiomyomas, or fibroids, are a major cause of abnormal uterine bleeding in women. American College of Obstetricians and Gynecologists, Agency for Healthcare Research and Quality, Cumulative Index to Nursing and Allied Health, Comparing Options for Management: Patient-Centered Results for Uterine Fibroids, International Federation of Gynecologists and Obstetricians, Magnetic resonance guided focused ultrasound, Population, Intervention, Comparators, Outcomes, Timing, Setting, Royal College of Obstetricians and Gynaecologists, Selective progesterone receptor modulator, Merck Serono (EMD Serono, Inc.), Rockland, MA, USA, AstraZeneca Pharmaceuticals, Wilmington, DE, USA, Eli Lilly and Company, Indianapolis, IN, USA. https://familydoctor.org/familydoctor/en/diseases-conditions/uterine-fibroids.html. Uterine Leiomyomata - StatPearls - NCBI Bookshelf If a woman does not want to have children, she can opt for endometrial ablation.

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