J Pharmacopuncture 2021;24(4):196-205. After the consistency begins to thicken, turn the mixer up a little bit. Study results revealed that pain intensity during active movement decreased an average of 95.2% in the group given comfrey ointment. View abstract. Comfrey is avoided on cuts or puncture wounds for this reason. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: Results of a randomized controlled clinical double-blind study. The FDA has recommended that all comfrey products that are taken by mouth be removed from the market. Documented adverse effects (the pyrrolizidine alkaloids, have substantial risk of causing fatal liver damage and can cause abortion). Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Phytomedicine. Consult your healthcare provider before using. Megan Nunn, PharmD, is a community pharmacist in Tennessee with over twelve years of experience in medication counseling and immunization. Buy 1 get 1 Half Price | Plus an extra 20% off 30, Shop buy 1 get 1 half price on all gut health products, Looking for fitness advice & inspiration this New Year? View abstract. A few studies show that comfrey cream may be helpful in the treatment of ankle sprains. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: Results of a double-blind, randomised, bicenter, placebo-controlled trial. Pabst H, Schaefer A, Staiger C, Junker-samek M, Predel HG. Browse our Sports Hub, Get 20% student discount with Student Beans, Discover the latest natural beauty products, Buy 1 get 1 Half Price on Vitamins & Supplements, Popular Vitamins & Supplements Subscriptions, Buy 1 get 1 Half Price gut health supplements, Guide to sleeping better natural sleeping remedies, Living in the now, gut health & mental wellbeing, The thing that makes you different makes you special, For the symptomatic relief of minor sprains and bruises, Contains Comfrey which is known for its healing properties.